Individuals with metabolic syndrome are at high risk for type 2 diabetes and cardiovascular disease. The ideal exercise prescription for these individuals, however, remains unclear. In addition, it is unknown if people taking medication during an exercise training program have different health responses compared with people exercise alone. This question is important given that several people with metabolic syndrome are recommended to take medicine to reduce disease risk. We are particularly interest in metformin interactions with exercise since it is the most prescribed medication to regulate blood glucose levels. Our study will therefore look at the role of exercise intensity training for 16 weeks, with or without metformin, in people with metabolic syndrome. We will screen all people to see if they qualify and measure: fitness, body composition, vascular health and blood flow as well as energy metabolism to better understand the optimal treatment plan to prevent disease progression. All people will receive supervised exercise session and parking at Rutgers. For more information, e-mail Jaclyn Dosik, M.Ed at